en
Scientific article
Open access
English

Association of lifecourse socioeconomic status with chronic inflammation and type 2 diabetes risk: the Whitehall II prospective cohort study

Published inPLOS Medicine, vol. 10, no. 7, e1001479
Publication date2013
Abstract

Socioeconomic adversity in early life has been hypothesized to "program" a vulnerable phenotype with exaggerated inflammatory responses, so increasing the risk of developing type 2 diabetes in adulthood. The aim of this study is to test this hypothesis by assessing the extent to which the association between lifecourse socioeconomic status and type 2 diabetes incidence is explained by chronic inflammation.

Keywords
  • Adult
  • Biomarkers/blood
  • C-Reactive Protein/metabolism
  • Cohort Studies
  • Diabetes Mellitus, Type 2/epidemiology/etiology
  • Female
  • Humans
  • Incidence
  • Inflammation/complications/epidemiology
  • Interleukin-6/blood
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk Factors
  • Social Class
  • United Kingdom/epidemiology
Affiliation Not a UNIGE publication
Citation (ISO format)
STRINGHINI, Silvia et al. Association of lifecourse socioeconomic status with chronic inflammation and type 2 diabetes risk: the Whitehall II prospective cohort study. In: PLOS Medicine, 2013, vol. 10, n° 7, p. e1001479. doi: 10.1371/journal.pmed.1001479
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal1549-1277
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