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Title

Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment

Authors
Thorball, Christian W
Borghesi, Alessandro
Bachmann, Nadine
Von Siebenthal, Chantal
Vongrad, Valentina
Turk, Teja
Neumann, Kathrin
Beerenwinkel, Niko
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Collaboration
Published in Journal of Acquired Immune Deficiency Syndromes. 2020, vol. 85, no. 4, p. 517-524
Abstract The primary hurdle for the eradication of HIV-1 is the establishment of a latent viral reservoir early after primary infection. Here, we investigated the potential influence of human genetic variation on the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment.
Keywords Anti-HIV Agents/therapeutic useGenetic Predisposition to DiseaseGenetic VariationGenomeHumanGenome-Wide Association StudyGenomics/methodsGenotypeHIV Infections/drug therapy/geneticsHIV-1HumansTime Factors
Identifiers
PMID: 33136754
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Structures
Research group Groupe Laurent Kaiser (virologie clinique) (668)
Citation
(ISO format)
THORBALL, Christian W et al. Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. In: Journal of Acquired Immune Deficiency Syndromes, 2020, vol. 85, n° 4, p. 517-524. doi: 10.1097/QAI.0000000000002473 https://archive-ouverte.unige.ch/unige:157059

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Deposited on : 2021-12-13

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