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Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment |
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Published in | Journal of Acquired Immune Deficiency Syndromes. 2020, vol. 85, no. 4, p. 517-524 | |
Abstract | The primary hurdle for the eradication of HIV-1 is the establishment of a latent viral reservoir early after primary infection. Here, we investigated the potential influence of human genetic variation on the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. | |
Keywords | Anti-HIV Agents/therapeutic use — Genetic Predisposition to Disease — Genetic Variation — Genome — Human — Genome-Wide Association Study — Genomics/methods — Genotype — HIV Infections/drug therapy/genetics — HIV-1 — Humans — Time Factors | |
Identifiers | PMID: 33136754 | |
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Research group | Groupe Laurent Kaiser (virologie clinique) (668) | |
Citation (ISO format) | THORBALL, Christian W et al. Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. In: Journal of Acquired Immune Deficiency Syndromes, 2020, vol. 85, n° 4, p. 517-524. doi: 10.1097/QAI.0000000000002473 https://archive-ouverte.unige.ch/unige:157059 |