Scientific article
English

Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment

Published inJournal of Acquired Immune Deficiency Syndromes, vol. 85, no. 4, p. 517-524
Publication date2020
Abstract

The primary hurdle for the eradication of HIV-1 is the establishment of a latent viral reservoir early after primary infection. Here, we investigated the potential influence of human genetic variation on the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment.

Keywords
  • Anti-HIV Agents/therapeutic use
  • Genetic Predisposition to Disease
  • Genetic Variation
  • Genome
  • Human
  • Genome-Wide Association Study
  • Genomics/methods
  • Genotype
  • HIV Infections/drug therapy/genetics
  • HIV-1
  • Humans
  • Time Factors
Citation (ISO format)
THORBALL, Christian W et al. Host genomics of the HIV-1 reservoir size and its decay rate during suppressive antiretroviral treatment. In: Journal of Acquired Immune Deficiency Syndromes, 2020, vol. 85, n° 4, p. 517–524. doi: 10.1097/QAI.0000000000002473
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Identifiers
Journal ISSN1525-4135
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