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Scientific article
English

Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV-1 transmission

CollaboratorsKaiser, Laurent
Published inHIV Medicine, vol. 22, no. 5, p. 346-359
Publication date2021
Abstract

Understanding the drivers of HIV-1 transmission is of importance for curbing the ongoing epidemic. Phylogenetic methods based on single viral sequences allow us to assess whether two individuals are part of the same viral outbreak, but cannot on their own assess who potentially transmitted the virus. We developed and assessed a molecular epidemiology method with the main aim to screen cohort studies for and to characterize individuals who are 'potential HIV-1 transmitters', in order to understand the drivers of HIV-1 transmission.

Keywords
  • HIV-1
  • Directionality of HIV-1 transmission
  • Molecular epidemiology
  • Phylogenetic
  • Transmission
Funding
  • Swiss National Science Foundation - BSSGIO_155851 to RDK
Citation (ISO format)
REICHMUTH, M L et al. Using longitudinally sampled viral nucleotide sequences to characterize the drivers of HIV-1 transmission. In: HIV Medicine, 2021, vol. 22, n° 5, p. 346–359. doi: 10.1111/hiv.13030
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1464-2662
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Creation09/21/2021 10:48:00 AM
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