Scientific article
Review
English

Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation

Published inEuropean Journal of Clinical Investigation, vol. 45, no. 3, p. 303-332
Publication date2015
Abstract

Following wider acceptance of 'the thrifty phenotype' hypothesis and the convincing evidence that early-life exposures can influence adult health even decades after the exposure, much interest has been placed on the mechanisms through which early-life exposures become biologically embedded.

Keywords
  • Adolescent
  • Adult
  • Aged
  • Aged
  • 80 and over
  • Body Mass Index
  • Child
  • Child Nutritional Physiological Phenomena/physiology
  • Child
  • Preschool
  • DNA Methylation/physiology
  • Disease Susceptibility/etiology
  • Environmental Exposure/adverse effects
  • Epigenesis
  • Genetic/physiology
  • Female
  • Humans
  • Infant
  • Life Change Events
  • Male
  • Middle Aged
  • Pediatric Obesity/complications
  • Risk Factors
  • Socioeconomic Factors
  • Young Adult
Affiliation entities Not a UNIGE publication
Citation (ISO format)
DEMETRIOU, Christiana A et al. Biological embedding of early-life exposures and disease risk in humans: a role for DNA methylation. In: European Journal of Clinical Investigation, 2015, vol. 45, n° 3, p. 303–332. doi: 10.1111/eci.12406
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0014-2972
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Update28/10/2024 15:40:55
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