Scientific article

Estimation of the global burden of disease attributable to contaminated sharps injuries among health-care workers

Published inAmerican Journal of Industrial Medicine, vol. 48, no. 6, p. 482-490
Publication date2005-12
First online date2005

Background: The global burden of hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) infection due to percutaneous injuries among health care workers (HCWs) is estimated. Methods: The incidence of infections attributable to percutaneous injuries in 14 geographical regions on the basis of the probability of injury, the prevalence of infection, the susceptibility of the worker, and the percutaneous transmission potential are modeled. The model also provides the attributable fractions of infection in HCWs. Results: Overall, 16,000 HCV, 66,000 HBV, and 1,000 HIV infections may have occurred in the year 2000 worldwide among HCWs due to their occupational exposure to percutaneous injuries. The fraction of infections with HCV, HBV, and HIV in HCWs attributable to occupational exposure to percutaneous injuries fraction reaches 39%, 37%, and 4.4% respectively. Conclusions: Occupational exposures to percutaneous injuries are substantial source of infections with bloodborne pathogens among health-care workers (HCWs). These infections are highly preventable and should be eliminated.

  • Needlestick injuries
  • Percutaneous injuries
  • Sharps injuries
  • Health care workers
  • HIV
  • HBV
  • HCV
  • Occupational disease
Affiliation Not a UNIGE publication
Citation (ISO format)
PRÜSS-ÜSTÜN, Annette, RAPITI AYLWARD, Elisabetta, HUTIN, Yvan. Estimation of the global burden of disease attributable to contaminated sharps injuries among health-care workers. In: American Journal of Industrial Medicine, 2005, vol. 48, n° 6, p. 482–490. doi: 10.1002/ajim.20230
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Article (Published version)
ISSN of the journal0271-3586

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