Deconvolution of sustained neural activity from large-scale calcium imaging data

Farouj, Younes; Karahanoglu, Fikret Isik; Van De Ville, Dimitri

doi:10.1109/TMI.2019.2942765

Scientific article

English

Deconvolution of sustained neural activity from large-scale calcium imaging data

ContributorsFarouj, Younes; Karahanoglu, Fikret Isik; Van De Ville, Dimitri

Published inIEEE Transactions on Medical Imaging, vol. 39, no. 4, p. 1094-1103

Publication date2020

Abstract

Recent technological advances in light-sheet microscopy make it possible to perform whole-brain functional imaging at the cellular level with the use of Ca2+ indicators. The outstanding spatial extent and resolution of this type of data open unique opportunities for understanding the complex organization of neuronal circuits across the brain. However, the analysis of this data remains challenging because the observed variations in fluorescence are, in fact, noisy indirect measures of the neuronal activity. [...]

Keywords

Temporal deconvolution
Light-sheet microscopy
Calcium imaging
Generalized total variation
ℓ₁-minimization

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

Research groups

Traitement d'images médicales (893)

Citation (ISO format)

FAROUJ, Younes, KARAHANOGLU, Fikret Isik, VAN DE VILLE, Dimitri. Deconvolution of sustained neural activity from large-scale calcium imaging data. In: IEEE Transactions on Medical Imaging, 2020, vol. 39, n° 4, p. 1094–1103. doi: 10.1109/TMI.2019.2942765

Article (Published version)

Identifiers

PID : unige:156917
DOI : 10.1109/TMI.2019.2942765
PMID : 31545714

Additional URL for this publicationhttps://ieeexplore.ieee.org/document/8846006/

Datasets

https://github.com/ufaro/CalciumDec

Journal ISSN0278-0062

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Deconvolution of sustained neural activity from large-scale calcium imaging data

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