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Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study

ContributorsWells, Philippa M; Adebayo, Adewale S; Bowyer, Ruth C E; Freidin, Maxim B; Finckh, Axelorcid; Strowig, Till; Lesker, Till Robin; Alpizar Rodriguez, Deshire; Gilbert, Benoît Thomas P.orcid; Kirkham, Bruce; Cope, Andrew P; Steves, Claire J; Williams, Frances M K
Published inThe Lancet. Rheumatology, vol. 2, no. 7, p. e418-e427
Publication date2020
Abstract

Rheumatoid arthritis is a chronic inflammatory autoimmune disease that is associated with reduced life expectancy. The disease is heritable and an extensive repertoire of genetic variants have been identified. The gut microbiota might represent an environmental risk factor for rheumatoid arthritis. We aimed to assess whether known rheumatoid arthritis risk alleles were associated with the gut microbiota in a large population who do not have rheumatoid arthritis.

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WELLS, Philippa M et al. Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study. In: The Lancet. Rheumatology, 2020, vol. 2, n° 7, p. e418–e427. doi: 10.1016/S2665-9913(20)30064-3
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Additional URL for this publicationhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729822/
Journal ISSN2665-9913
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