Scientific article
English

Specificity and modularity of flagellin nonulosonic acid glycosyltransferases

Publication date2021-11-12
First online date2021-11-12
Abstract

Many bacterial flagella are specifically O-glycosylated with nonulosonic acids, including the sialic acid derivatives, pseudaminic acid or legionaminic acid. Unlike protein glycosyltransferases that are extracytoplasmic, flagellin glycosyltransferases (fGTs) act cytoplasmically with unknown donor or acceptor specificities. The recent reconstitution of fGT-based glycosylation in heterologous hosts enables analyses underpinning such specificity.

Keywords
  • FlmG
  • Maf
  • Flagellin
  • Glycosylation
  • Legionaminic acid
  • Pseudaminic acid
Citation (ISO format)
KINT, Nicolas, UNAY, Jovelyn, VIOLLIER, Patrick. Specificity and modularity of flagellin nonulosonic acid glycosyltransferases. In: Trends in microbiology, 2021. doi: 10.1016/j.tim.2021.10.005
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0966-842X
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Technical informations

Creation17/11/2021 18:50:00
First validation17/11/2021 18:50:00
Update time16/03/2023 01:57:40
Status update16/03/2023 01:57:39
Last indexation31/10/2024 23:58:33
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