en
Scientific article
Review
English

Is there a role for childhood vaccination against COVID-19?

Published inPediatric allergy and immunology, vol. 32, no. 1, p. 9-16
Publication date2021-01
First online date2020-10-08
Abstract

Tremendous efforts are undertaken to quickly develop COVID-19 vaccines that protect vulnerable individuals from severe disease and thereby limit the health and socioeconomic impacts of the pandemic. Potential candidates are tested in adult populations, and questions arise of whether COVID-19 vaccination should be implemented in children. Compared to adults, the incidence and disease severity of COVID-19 are low in children, and despite their infectiveness, their role in disease propagation is limited. Therefore, COVID-19 vaccines will need to have fully demonstrated safety and efficacy in preventing not only complications but transmission to justify childhood vaccination. This work summarizes currently tested vaccine platforms and debates practical and ethical considerations for their potential use in children. It also discusses the already deleterious effect of the pandemic on routine childhood vaccine coverage, calling for action to limit the risks for a rise in vaccine-preventable diseases.

eng
Keywords
  • COVID-19
  • COVID-19 vaccines
  • Childhood vaccination
  • Efficacy
  • Safety
  • Transmission of disease
  • Adolescent
  • COVID-19 / prevention & control
  • COVID-19 Vaccines / adverse effects
  • COVID-19 Vaccines / therapeutic use
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Pandemics / prevention & control
  • Risk Factors
  • SARS-CoV-2 / immunology
  • Vaccination / ethics
  • Vaccination / methods
  • Vaccines, DNA / therapeutic use
  • Vaccines, Synthetic / therapeutic use
Citation (ISO format)
EBERHARDT, Christiane Sigrid, SIEGRIST, Claire-Anne. Is there a role for childhood vaccination against COVID-19? In: Pediatric allergy and immunology, 2021, vol. 32, n° 1, p. 9–16. doi: 10.1111/pai.13401
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0905-6157
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Technical informations

Creation09/30/2021 7:57:00 AM
First validation09/30/2021 7:57:00 AM
Update time03/16/2023 1:50:40 AM
Status update03/16/2023 1:50:40 AM
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