Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin

Svendsen, Henrik A; Meling, Torstein; Nygaard, Vigdis; Waagene, Stein; Russnes, Hege; Juell, Siri; Rogne, Siril G; Pahnke, Jens; Helseth, Eirik; Fodstad, Øystein; Maelandsmo, Gunhild M

doi:10.1002/cam4.4334

Scientific article

English

Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin

ContributorsSvendsen, Henrik A; Meling, Torstein; Nygaard, Vigdis; Waagene, Stein; Russnes, Hege; Juell, Siri; Rogne, Siril G; Pahnke, Jens; Helseth, Eirik; Fodstad, Øystein; Maelandsmo, Gunhild M

Published inCancer Medicine

Publication date2021

Abstract

Malignant melanomas frequently metastasize to the brain, but metastases in the cerebellum are underrepresented compared with metastases in the cerebrum.

Keywords

Athymic nude fox1nu mice
Brain metastasis model
Human melanoma
Site specificity
Tissue- specific metastasis

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Research groups

Groupe Schaller Karl Lothard (neurochirurgie) (851)

Citation (ISO format)

SVENDSEN, Henrik A et al. Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin. In: Cancer Medicine, 2021. doi: 10.1002/cam4.4334

Article (Published version)

CC BY

Identifiers

PID : unige:156444
DOI : 10.1002/cam4.4334
PMID : 34612023

Journal ISSN2045-7634

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Creation17/10/2021 18:23:00

First validation17/10/2021 18:23:00

Update16/03/2023 01:49:54

Status update16/03/2023 01:49:53

Last indexation31/10/2024 23:49:05

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Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin

Malignant melanomas frequently metastasize to the brain, but metastases in the cerebellum are underrepresented compared with metastases in the cerebrum.

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