We commend Dr. Villanueva and colleagues for their Cosmetic article “Staying Safe during Gluteal Fat Transplantation” published in the January of 2018 issue of the Journal.1 This outstanding panel of leaders in plastic surgery recommended proper patient selection, favorable instrumentation, correct patient positioning, proper technique (i.e., continual motion and knowledge of cannula location at all times), and adequate knowledge of anatomy (i.e., superficial planes of injection and avoidance of excessively high recipient-site pressure) as ways of avoiding fat embolism in fat grafting gluteal augmentation.1 The worldwide ever-increasing number of procedures performed, associated with the rate of fatalities related to fat embolism (which is the highest in the field of aesthetic surgery), demonstrate the tremendous relevance of this article.1–4 Indeed, as the authors observe in their article, surgeons with a large number of cases did not observe this complication, suggesting that faithful adherence to the above-mentioned key points is pivotal for guaranteeing safety.