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Title

Spinal Meningiomas: Influence of Cord Compression and Radiological Features on Preoperative Functional Status and Outcome

Authors
Baro, Valentina
Moiraghi, Alessandro
Carlucci, Valentina
Paun, Luca
Anglani, Mariagiulia
Ermani, Mario
Saladino, Andrea
Chioffi, Franco
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Published in Cancers. 2021, vol. 13, no. 16, 4183
Abstract Patients affected by spinal meningioma globally exhibit an excellent postoperative functional outcome despite tumor size and severity of spinal cord compression. This work aims to analyze the impact of tumor size and other radiological findings on clinical functional preoperative status and postoperative outcome. In this multicentric retrospective study involving 90 adult patients, we found that spinal cord and tumor occupancy as well as cord compression and tumor volume are correlated with low preoperative functional status. Higher tumor occupancy and tumor-canal volume ratio corresponded to lower postoperative neurological recovery. Cord re-expansion did not show any correlation with postoperative outcome, while preoperative signs of cord myelopathy were predictors of worse postoperative outcome. These findings suggest that these radiological features should be taken into consideration during preoperative counselling.
Keywords McCormick scaleCord compressionFunctional outcomeMagnetic resonance imagingSpinal meningiomaTumor volume
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PMID: 34439337
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Research group Groupe Schaller Karl Lothard (neurochirurgie) (851)
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BARO, Valentina et al. Spinal Meningiomas: Influence of Cord Compression and Radiological Features on Preoperative Functional Status and Outcome. In: Cancers, 2021, vol. 13, n° 16, p. 4183. doi: 10.3390/cancers13164183 https://archive-ouverte.unige.ch/unige:155139

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Deposited on : 2021-10-04

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