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Scientific article
OA Policy
English

Persistence of anti-SARS-CoV-2 antibodies: immunoassay heterogeneity and implications for serosurveillance

Contributors

Perez-Saez, Javier; Zaballa, Maria-Eugenia; Yerly Ferrillo, Sabine; Andrey, Diego Olivier; Meyer, Benjamin; Eckerle, Isabella Anne; Balavoine, Jean-François; Chappuis, François; Pittet, Didier; Trono, Didier; Kherad, Omar; Vuilleumier, Nicolas; Kaiser, Laurent; Guessous, Idris; Stringhini, Silvia; Azman, Andrew

Published in

Clinical Microbiology and Infection

Publication date

2021

Abstract

Serological studies have been critical in tracking the evolution of the COVID-19 pandemic. Data on anti-SARS-CoV-2 antibodies persistence remain sparse, especially from infected individuals with few to no symptoms. The objective of the study was to quantify the sensitivity for detecting historic SARS-CoV-2 infections as a function of time since infection for three commercially available SARS-CoV-2 immunoassays and to explore the implications of decaying immunoassay sensitivity in estimating seroprevalence.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

PEREZ-SAEZ, Javier et al. Persistence of anti-SARS-CoV-2 antibodies: immunoassay heterogeneity and implications for serosurveillance. In: Clinical Microbiology and Infection, 2021. doi: 10.1016/j.cmi.2021.06.040

Main files (1)

Article (Published version)
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Secondary files (1)

Supplemental data
CC BY

Identifiers

Journal ISSN

1198-743X
313views
380downloads

Technical informations

Creation

20/09/2021 10:52:00

First validation

20/09/2021 10:52:00

Update

10/02/2026 08:15:53

Status update

10/02/2026 08:15:53

Last indexation

10/02/2026 08:18:28
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