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Scientific article
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English

Validity and reliability of the CatWalk system as a static and dynamic gait analysis tool for the assessment of functional nerve recovery in small animal models

Published inBrain and Behavior, vol. 7, no. 7, e00723
Publication date2017
Abstract

A range of behavioral testing paradigms have been developed for the research of central and peripheral nerve injuries with the help of small animal models. Following any nerve repair strategy, improved functional outcome may be the most important evidence of axon regeneration. A novel automated gait analysis system, the CatWalk™, can measure dynamic as well as static gait patterns of small animals. Of most interest in detecting functional recovery are in particular dynamic gait parameters, coordination measures, and the intensity of the animals paw prints. This article is designed to lead to a more efficient choice of CatWalk parameters in future studies concerning the functional evaluation of nerve regeneration and simultaneously add to better interstudy comparability.

Keywords
  • Automated gait analysis system
  • Dynamic and static gait parameters
  • Peripheral nerve regeneration
  • Rat and mouse sciatic nerve
Affiliation Not a UNIGE publication
Funding
  • Swiss National Science Foundation - #31003A_133076/1
Citation (ISO format)
KAPPOS, Elisabeth A et al. Validity and reliability of the CatWalk system as a static and dynamic gait analysis tool for the assessment of functional nerve recovery in small animal models. In: Brain and Behavior, 2017, vol. 7, n° 7, p. e00723. doi: 10.1002/brb3.723
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Article (Published version)
Identifiers
ISSN of the journal2162-3279
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Technical informations

Creation03/23/2021 4:21:00 PM
First validation03/23/2021 4:21:00 PM
Update time03/16/2023 6:17:57 AM
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