en
Scientific article
Review
Open access
French

Empreinte génomique, la bataille des sexes ?

ContributorsGiacobino, Ariane
Published inRevue médicale suisse, vol. 1, no. 25, p. 1687-1690
Publication date2005
Abstract

It is estimated that 100 to 200 genes in the human genome are imprinted. These are expressed only from one parental allele, although having the same DNA sequence. Several of the known imprinted genes have been shown to be involved in fetal and placental growth, and imprinting defects can lead to embryonic, developmental defects as well as cancer. This mechanism of gene regulation probably emerged 150 million years ago in mammals. The reasons for the appearance and maintenance of this phenomenon throughout evolution are still controversial.

Keywords
  • Animals
  • Biological Evolution
  • Cell Transformation
  • Neoplastic/genetics
  • Genomic Imprinting
  • Humans
  • Neoplasms/genetics
  • Parents
Affiliation Not a UNIGE publication
Citation (ISO format)
GIACOBINO, Ariane. Empreinte génomique, la bataille des sexes ? In: Revue médicale suisse, 2005, vol. 1, n° 25, p. 1687–1690.
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1660-9379
88views
17downloads

Technical informations

Creation02/03/2021 2:50:00 PM
First validation02/03/2021 2:50:00 PM
Update time03/16/2023 1:20:45 AM
Status update03/16/2023 1:20:44 AM
Last indexation01/17/2024 2:17:26 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack