A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress
Published inNature Communications, vol. 12, no. 1, 4484
Publication date2021
Abstract
Keywords
- Animals
- Genetically Modified
- Connexins/genetics/metabolism
- Embryo
- Nonmammalian/cytology/embryology/metabolism
- Gene Expression Regulation
- Developmental
- Hematopoietic Stem Cells/cytology/metabolism
- Humans
- Microscopy
- Confocal
- Mutation
- Oxidative Stress
- Oxidoreductases Acting on Sulfur Group Donors/genetics/metabolism
- Signal Transduction/genetics
- Stem Cell Niche
- Time-Lapse Imaging/methods
- Zebrafish/embryology/genetics
- Zebrafish Proteins/genetics/metabolism
Funding
- Swiss National Science Foundation - 31003_166515
- Swiss National Science Foundation - Hematopoietic Stem Cells and their niche: origin and maturation during embryonic development [310030_184814]
Citation (ISO format)
CACIALLI, Pietro et al. A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress. In: Nature Communications, 2021, vol. 12, n° 1, p. 4484. doi: 10.1038/s41467-021-24831-0
Main files (1)
Article (Published version)
Secondary files (12)
Identifiers
- PID : unige:154572
- DOI : 10.1038/s41467-021-24831-0
- PMID : 34301940
ISSN of the journal2041-1723