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Scientific article
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English

Aberrant striatal coupling with default mode and central executive network relates to self-reported avolition and anhedonia in schizophrenia

Publication date2020
Abstract

Avolition and anhedonia are common symptoms in schizophrenia and are related to poor long-term prognosis. There is evidence for aberrant cortico-striatal function and connectivity as neural substrate of avolition and anhedonia. However, it remains unclear how both relate to shared or distinct striatal coupling with large-scale intrinsic networks. Using resting state functional magnetic resonance imaging (rs-fMRI) this study investigated the association of large-scale cortico-striatal functional connectivity with self-reported and clinician-rated avolition and anhedonia in subjects with schizophrenia.

Citation (ISO format)
BRAKOWSKI, Janis et al. Aberrant striatal coupling with default mode and central executive network relates to self-reported avolition and anhedonia in schizophrenia. In: Journal of Psychiatric Research, 2020. doi: 10.1016/j.jpsychires.2020.10.047
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ISSN of the journal0022-3956
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