Hypoxemia in COVID-19; Comment on: "The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients"

Coen, Matteo; Allali, Gilles; Adler, Dan Elie; Serratrice, Jacques

doi:10.1002/jmv.26020

Scientific article

Comment

English

Hypoxemia in COVID-19; Comment on: "The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients"

ContributorsCoen, Matteo

; Allali, Gilles; Adler, Dan Elie; Serratrice, Jacques

Published inJournal of Medical Virology, vol. 92, no. 10, p. 1705-1706

Publication date2020

Abstract

Patients with coronavirus disease 2019 (COVID-19) seldom complain of dyspnea. It has been suggested that the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) targets the brainstem and plays a role COVID-19 respiratory failure. We hypothesise that asymptomatic hypoxemia presented by COVID-19 patients with severe pneumonia is related to a dysfunction of cortical rather than of subcortical structures, and is linked to SARS-CoV-2 neuroinvasiveness. Comment on: Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol. 2020 Jun;92(6):552-555. doi: 10.1002/jmv.25728. Epub 2020 Mar 11. PMID: 32104915; PMCID: PMC7228394.

Keywords

Coronavirus
Dissemination
Nervous system
Pathogenesis
Virus classification

Affiliation entities

Research groups

Groupe Gasche-Soccal Paola (958)

Citation (ISO format)

COEN, Matteo et al. Hypoxemia in COVID-19; Comment on: ‘The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients’. In: Journal of Medical Virology, 2020, vol. 92, n° 10, p. 1705–1706. doi: 10.1002/jmv.26020

Article (Accepted version)

Article (Published version)

Identifiers

PID : unige:153506
DOI : 10.1002/jmv.26020
PMID : 32418237

Additional URL for this publicationhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276823/

Journal ISSN0146-6615

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Creation15/10/2020 14:41:00

First validation15/10/2020 14:41:00

Update16/03/2023 00:58:06

Status update16/03/2023 00:58:06

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Hypoxemia in COVID-19; Comment on: "The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients"

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