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Hypoxemia in COVID-19; Comment on: "The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients"

Published inJournal of Medical Virology, vol. 92, no. 10, p. 1705-1706
Publication date2020
Abstract

Patients with coronavirus disease 2019 (COVID-19) seldom complain of dyspnea. It has been suggested that the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) targets the brainstem and plays a role COVID-19 respiratory failure. We hypothesise that asymptomatic hypoxemia presented by COVID-19 patients with severe pneumonia is related to a dysfunction of cortical rather than of subcortical structures, and is linked to SARS-CoV-2 neuroinvasiveness. Comment on: Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol. 2020 Jun;92(6):552-555. doi: 10.1002/jmv.25728. Epub 2020 Mar 11. PMID: 32104915; PMCID: PMC7228394.

Keywords
  • Coronavirus
  • Dissemination
  • Nervous system
  • Pathogenesis
  • Virus classification
Citation (ISO format)
COEN, Matteo et al. Hypoxemia in COVID-19; Comment on: ‘The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients’. In: Journal of Medical Virology, 2020, vol. 92, n° 10, p. 1705–1706. doi: 10.1002/jmv.26020
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ISSN of the journal0146-6615
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Technical informations

Creation10/15/2020 2:41:00 PM
First validation10/15/2020 2:41:00 PM
Update time03/16/2023 12:58:06 AM
Status update03/16/2023 12:58:06 AM
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