A Short, Simple Synthesis of (±)-Monomorine

Jefford, Charles; Tang, Qian; Zaslona, Alexander Tadeusz

doi:10.1002/hlca.19890720812

Scientific article

English

A Short, Simple Synthesis of (±)-Monomorine

ContributorsJefford, Charles; Tang, Qian; Zaslona, Alexander Tadeusz

Published inHelvetica Chimica Acta, vol. 72, no. 8, p. 1749-1752

Publication date1989

Abstract

Racemic monomorine (12) is prepared in six steps in 26% overall yield from 2-butyl-1H-pyrrole and ethyl (E)-but-2-enoate by exploiting the rhodium(II)-acetate-catalyzed decomposition of (4RS)-4-(2′-butyl-1′ H-pyrrol-1′-yl)-1-diazopentan-2-one (7).

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

JEFFORD, Charles, TANG, Qian, ZASLONA, Alexander Tadeusz. A Short, Simple Synthesis of (±)-Monomorine. In: Helvetica Chimica Acta, 1989, vol. 72, n° 8, p. 1749–1752. doi: 10.1002/hlca.19890720812

Article (Published version)

Identifiers

PID : unige:152901
DOI : 10.1002/hlca.19890720812

Additional URL for this publicationhttps://onlinelibrary.wiley.com/doi/10.1002/hlca.19890720812

Journal ISSN0018-019X

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A Short, Simple Synthesis of (±)-Monomorine

Racemic monomorine (12) is prepared in six steps in 26% overall yield from 2-butyl-1H-pyrrole and ethyl (E)-but-2-enoate by exploiting the rhodium(II)-acetate-catalyzed decomposition of (4RS)-4-(2′-butyl-1′ H-pyrrol-1′-yl)-1-diazopentan-2-one (7).

Technical informations