The pseudo-enzymatic action of tri-o-thymotide clathrates applied to the determination of the absolute configuration of four halohydrins

Gerdil, Raymond; Barchietto, Giacomo

doi:10.1016/S0040-4039(00)70648-4

Scientific article

Letter

English

The pseudo-enzymatic action of tri-o-thymotide clathrates applied to the determination of the absolute configuration of four halohydrins

ContributorsGerdil, Raymond; Barchietto, Giacomo

Published inTetrahedron Letters, vol. 30, no. 48, p. 6677-6678

Publication date1989

Abstract

The heterogeneous reactions of gaseous HCl and HBr, as external agents, with trans-2,3-dimethyloxirane and 2,2,3-trimethyloxirane as guest molecules in tri-o-thymotide clathrates are shown to allow the ready determination of the absolute configuration of the end-products owing to highly specific host-reactant interactions. Heterogenous reactions of hydrogenhalides (gas) with TOT-enclathrated methyloxiranes allow the absolute configuration assignment of the product owing to highly specific host-reactant interactions.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

GERDIL, Raymond, BARCHIETTO, Giacomo. The pseudo-enzymatic action of tri-o-thymotide clathrates applied to the determination of the absolute configuration of four halohydrins. In: Tetrahedron Letters, 1989, vol. 30, n° 48, p. 6677–6678. doi: 10.1016/S0040-4039(00)70648-4

Article (Published version)

Identifiers

PID : unige:152735
DOI : 10.1016/S0040-4039(00)70648-4

Additional URL for this publicationhttps://linkinghub.elsevier.com/retrieve/pii/S0040403900706484

Journal ISSN0040-4039

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The pseudo-enzymatic action of tri-o-thymotide clathrates applied to the determination of the absolute configuration of four halohydrins

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