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Anti-Apolipoprotein A-1 IgG Influences Neutrophil Extracellular Trap Content at Distinct Regions of Human Carotid Plaques

Published inInternational Journal of Molecular Sciences, vol. 21, no. 20, 7721
Publication date2020
Abstract

Neutrophils accumulate in atherosclerotic plaques. Neutrophil extracellular traps (NET) were recently identified in experimental atherosclerosis and in complex human lesions. However, not much is known about the NET marker citrullinated histone-3 (H3Cit) expression and functionality in human carotid plaques. Moreover, the association between the proatherosclerotic autoantibody anti-apolipoprotein A-1 (anti-ApoA-1 IgG) and NET has never been investigated.

Keywords
  • Atherosclerosis
  • Vulnerable plaques
  • Anti-apoA-1 IgG
  • Neutrophil extracellular traps
Citation (ISO format)
DA SILVA, Rafaela et al. Anti-Apolipoprotein A-1 IgG Influences Neutrophil Extracellular Trap Content at Distinct Regions of Human Carotid Plaques. In: International Journal of Molecular Sciences, 2020, vol. 21, n° 20, p. 7721. doi: 10.3390/ijms21207721
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ISSN of the journal1661-6596
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Creation11/04/2020 11:42:00 AM
First validation11/04/2020 11:42:00 AM
Update time03/16/2023 12:47:44 AM
Status update03/16/2023 12:47:43 AM
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