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Scientific article
Letter
English

Enantioselective addition of (Z)- and (E)-alkenylzinc bromides to aldehydes: asymmetric synthesis of sec-allylalcohols

Published inTetrahedron Letters, vol. 32, no. 41, p. 5777-5780
Publication date1991
Abstract

In situ prepared (Z)- and (E)-1-alkenylzinc bromides 5 were added to various aldehydes 1 in the presence of lithiated (+)-N-methylephedrine or (+)-2-(N,N-dimethylamino)-1,2-diphenylethanol to give sec. allyalcohols 7 in high optical purity with simple recovery of the chiral aminol 6.

Citation (ISO format)
VON OPPOLZER, Wolfgang, RADINOV, Roumen Nikolaev. Enantioselective addition of (Z)- and (E)-alkenylzinc bromides to aldehydes: asymmetric synthesis of sec-allylalcohols. In: Tetrahedron Letters, 1991, vol. 32, n° 41, p. 5777–5780. doi: 10.1016/S0040-4039(00)93553-6
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ISSN of the journal0040-4039
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