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Title

Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging

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Published in Neuroradiology. 2021
Abstract Cortical microinfarcts (CMI) are increasingly recognized in the neurological community as a biomarker related to cognitive impairment and dementia. If their radiological depiction has been largely described in experimental settings using ultra-high-field magnetic resonance imaging (MRI), less is known about their visibility on routinely used 3-T MRI. In this radiologic-pathologic correlation study, using 3-T post-mortem MRI, we searched for hippocampal CMI, in a double-blinded fashion, and found that only 4/36, or 11%, were clearly demonstrated on both radiological and histopathological exams.
Keywords Cerebral microinfarctsHippocampusDementia3-T post-mortem MRIHistopathology
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PMID: 33909116
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Article (Published version) (608 Kb) - public document Free access
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Research group Neuroimagerie moléculaire en psychiatrie (983)
Project FNS: 320030_159990/1
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SCHEFFLER, Max et al. Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging. In: Neuroradiology, 2021. doi: 10.1007/s00234-021-02717-8 https://archive-ouverte.unige.ch/unige:152335

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Deposited on : 2021-06-11

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