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Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging |
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Published in | Neuroradiology. 2021 | |
Abstract | Cortical microinfarcts (CMI) are increasingly recognized in the neurological community as a biomarker related to cognitive impairment and dementia. If their radiological depiction has been largely described in experimental settings using ultra-high-field magnetic resonance imaging (MRI), less is known about their visibility on routinely used 3-T MRI. In this radiologic-pathologic correlation study, using 3-T post-mortem MRI, we searched for hippocampal CMI, in a double-blinded fashion, and found that only 4/36, or 11%, were clearly demonstrated on both radiological and histopathological exams. | |
Keywords | Cerebral microinfarcts — Hippocampus — Dementia — 3-T post-mortem MRI — Histopathology | |
Identifiers | PMID: 33909116 | |
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Research group | Neuroimagerie moléculaire en psychiatrie (983) | |
Project | Swiss National Science Foundation: 320030_159990 | |
Citation (ISO format) | SCHEFFLER, Max et al. Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging. In: Neuroradiology, 2021. doi: 10.1007/s00234-021-02717-8 https://archive-ouverte.unige.ch/unige:152335 |