The alkylation of Silyl Enol Ethers with S<sub>N</sub>1-Unreactive Iodides in the Presence of Silver Trifluoroacetate

Jefford, Charles; Sledeski, Adam; Lelandais, Patrick Jean; Boukouvalas, John

doi:10.1016/S0040-4039(00)74160-8

Scientific article

Letter

English

The alkylation of Silyl Enol Ethers with S_N1-Unreactive Iodides in the Presence of Silver Trifluoroacetate

ContributorsJefford, Charles; Sledeski, Adam; Lelandais, Patrick Jean; Boukouvalas, John

Published inTetrahedron Letters, vol. 33, no. 14, p. 1855-1858

Publication date1992

Abstract

Silyl enol ethers can be effectively alkylated with primary n-alkyl iodides in the presence of silver trifluoro-acetate to give monoalkyl ketones. Moderate yields of monoalkyl ketones are obtained by alkylating silyl enol ethers with primary n-alkyl iodides in the presence of silver trifluoroacetate.

Keywords

Alkylalion
n-alkyl iodide
Silver trifluoroacetate
Silyl enol ether

Affiliation

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Funding

Swiss National Science Foundation - 20-27'966.89

Citation (ISO format)

JEFFORD, Charles et al. The alkylation of Silyl Enol Ethers with S<sub>N</sub>1-Unreactive Iodides in the Presence of Silver Trifluoroacetate. In: Tetrahedron Letters, 1992, vol. 33, n° 14, p. 1855–1858. doi: 10.1016/S0040-4039(00)74160-8

Article (Published version)

Identifiers

PID : unige:152048
DOI : 10.1016/S0040-4039(00)74160-8

Commercial URLhttps://linkinghub.elsevier.com/retrieve/pii/S0040403900741608

ISSN of the journal0040-4039

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The alkylation of Silyl Enol Ethers with SN1-Unreactive Iodides in the Presence of Silver Trifluoroacetate

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The alkylation of Silyl Enol Ethers with S_N1-Unreactive Iodides in the Presence of Silver Trifluoroacetate