en
Scientific article
Letter
English

An Enantiospecific Synthesis of β-Amino Acids

Published inTetrahedron Letters, vol. 34, no. 7, p. 1111-1114
Publication date1993
Abstract

L-Aspartic acid by regioselective modification of the α-carboxylic acid group, namely N-tosylation, anhydride formation, reduction, iodo-esterification, alkylation, and deprotection afforded a series of γ-alkyl β-aminobutyric acids of the R configuration (ee>99%).

Keywords
  • Aspartic acid
  • N-camphanoyl ester
  • Enantiomeric purity
Funding
  • Swiss National Science Foundation - 20-32166.91
Citation (ISO format)
JEFFORD, Charles, WANG, Jian Bo. An Enantiospecific Synthesis of β-Amino Acids. In: Tetrahedron Letters, 1993, vol. 34, n° 7, p. 1111–1114. doi: 10.1016/S0040-4039(00)77503-4
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Article (Published version)
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Identifiers
ISSN of the journal0040-4039
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