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Title

Seroprevalence and placental transmission of maternal antibodies specific for Neisseria meningitidis Serogroups A, C, Y and W135 and influence of maternal antibodies on the immune response to a primary course of MenACWY-CRM vaccine in the United Kingdom

Authors
Snape, Matthew D
Kelly, Dominic F
O'Connor, Daniel
John, Tessa
Kibwana, Elizabeth
Parks, Hannah
Ford, Karen
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Published in Pediatric Infectious Disease Journal. 2013, vol. 32, no. 7, p. 768-776
Abstract Maternal antibodies give neonates some protection against bacterial infection. We measured antibodies against Neisseria meningitidis serogroups A, C, Y and W135 in mothers and their 2-month-old infants at study enrollment. We also assessed the impact of maternal antibody present at 2 months of age on the immune response to a primary course of quadrivalent meningococcal conjugate vaccine (MenACWY-CRM197) given at 2 and 4 months of age.
Keywords Antibodies, Bacterial/bloodB-Lymphocytes/chemistry/immunologyFemaleHumansImmunity, Maternally-AcquiredImmunologic MemoryInfantMeningococcal Vaccines/administration & dosage/immunologyNeisseria meningitidis/immunologyPlacenta/metabolismPregnancySeroepidemiologic StudiesUnited KingdomVaccination/methods
Identifiers
PMID: 23538521
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Research group Recherche en infectiologie pédiatrique et en pédiatrie générale (853)
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BLANCHARD ROHNER, Géraldine et al. Seroprevalence and placental transmission of maternal antibodies specific for Neisseria meningitidis Serogroups A, C, Y and W135 and influence of maternal antibodies on the immune response to a primary course of MenACWY-CRM vaccine in the United Kingdom. In: Pediatric Infectious Disease Journal, 2013, vol. 32, n° 7, p. 768-776. doi: 10.1097/INF.0b013e318292f425 https://archive-ouverte.unige.ch/unige:151760

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Deposited on : 2021-05-18

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