Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation

Petersdorf, Effie W; Bengtsson, Mats; De Santis, Dianne; Dubois, Valerie; Fleischhauer, Katharina; Gooley, Ted; Horowitz, Mary; Madrigal, J Alejandro; Malkki, Mari; McKallor, Caroline; Morishima, Yasuo; Oudshoorn, Machteld; Spellman, Stephen R; Villard, Jean; Stevenson, Phil; Carrington, Mary; The International Histocompatibility Working Group in Hematopoietic-Cell Transplantation

doi:10.1200/JCO.20.00265

Scientific article

English

Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation

ContributorsPetersdorf, Effie W; Bengtsson, Mats; De Santis, Dianne; Dubois, Valerie; Fleischhauer, Katharina; Gooley, Ted; Horowitz, Mary; Madrigal, J Alejandro; Malkki, Mari; McKallor, Caroline; Morishima, Yasuo; Oudshoorn, Machteld; Spellman, Stephen R; Villard, Jean; Stevenson, Phil; Carrington, Mary; The International Histocompatibility Working Group in Hematopoietic-Cell Transplantation

Published inJournal of Clinical Oncology, vol. 38, no. 24, p. 2712-2718

Publication date2020

Abstract

The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell transplantation (HCT) from HLA-A, -B, -C, -DRB1, -DQB1-matched and -mismatched unrelated donors.

Affiliation

Faculté de médecine / Section de médecine clinique / Département de médecine

Research group

Transplantation immunologie et osteoimmunologie (561)

Funding

Swiss National Science Foundation - New insights in the immunogenetics of haematopoietic stem cell transplantation [310030_173237]

Citation (ISO format)

PETERSDORF, Effie W et al. Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation. In: Journal of Clinical Oncology, 2020, vol. 38, n° 24, p. 2712–2718. doi: 10.1200/JCO.20.00265

Article (Published version)

Identifiers

PID : unige:151722
DOI : 10.1200/JCO.20.00265
PMID : 32479188

Commercial URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430213/

ISSN of the journal0732-183X

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Role of HLA-DP Expression in Graft-Versus-Host Disease After Unrelated Donor Transplantation

The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell transplantation (HCT) from HLA-A, -B, -C, -DRB1, -DQB1-matched and -mismatched unrelated donors.

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