Rapid immunochromatographic tests for the diagnosis of chronic Chagas disease in at-risk populations: A systematic review and meta-analysis

Angheben, Andrea; Buonfrate, Dora; Cruciani, Mario; Jackson, Yves-Laurent Julien; Alonso-Padilla, Julio; Gascon, Joaquim; Gobbi, Federico; Giorli, Giovanni; Anselmi, Mariella; Bisoffi, Zeno

doi:10.1371/journal.pntd.0007271

Scientific article

Meta-analysis

English

Rapid immunochromatographic tests for the diagnosis of chronic Chagas disease in at-risk populations: A systematic review and meta-analysis

ContributorsAngheben, Andrea; Buonfrate, Dora; Cruciani, Mario; Jackson, Yves-Laurent Julien

; Alonso-Padilla, Julio; Gascon, Joaquim; Gobbi, Federico; Giorli, Giovanni; Anselmi, Mariella; Bisoffi, Zeno

Published inPLOS Neglected Tropical Diseases, vol. 13, no. 5, e0007271

Publication date2019

Abstract

Despite of a high disease burden, mainly in Latin America, Chagas disease (CD) is underdiagnosed and undertreated. Rapid diagnostic tests (RDTs) might improve the access to diagnosis. The aim of this study is to review the accuracy of commercially available RDTs used in field conditions for the diagnosis of chronic CD in populations at risk, in endemic and non-endemic countries.

Keywords

Case-Control Studies
Chagas Disease
Chagas Disease/diagnosis/parasitology
Cohort Studies
Diagnostic Tests
Routine/methods
Humans
Immunoassay/methods
Sensitivity and Specificity
Trypanosoma cruzi/genetics/isolation & purification

Affiliation entities

Citation (ISO format)

ANGHEBEN, Andrea et al. Rapid immunochromatographic tests for the diagnosis of chronic Chagas disease in at-risk populations: A systematic review and meta-analysis. In: PLOS Neglected Tropical Diseases, 2019, vol. 13, n° 5, p. e0007271. doi: 10.1371/journal.pntd.0007271