How geographic access to care shapes disease burden: The current impact of post-exposure prophylaxis and potential for expanded access to prevent human rabies deaths in Madagascar

Rajeev, Malavika; Guis, Hélène; Edosoa, Glenn Torrencelli; Hanitriniaina, Chantal; Randrianarijaona, Anjasoa; Mangahasimbola, Reziky Tiandraza; Hierink, Fleur; Ramiandrasoa, Ravo; Nely, José; Heraud, Jean-Michel; Andriamandimby, Soa Fy; Baril, Laurence; Metcalf, C. Jessica E.; Hampson, Katie

doi:10.1371/journal.pntd.0008821

Scientific article

Open access

English

How geographic access to care shapes disease burden: The current impact of post-exposure prophylaxis and potential for expanded access to prevent human rabies deaths in Madagascar

ContributorsRajeev, Malavika; Guis, Hélène; Edosoa, Glenn Torrencelli; Hanitriniaina, Chantal; Randrianarijaona, Anjasoa; Mangahasimbola, Reziky Tiandraza; Hierink, Fleur

; Ramiandrasoa, Ravo; Nely, José; Heraud, Jean-Michel; Andriamandimby, Soa Fy; Baril, Laurence; Metcalf, C. Jessica E.; Hampson, Katie

Published inPLOS Neglected Tropical Diseases, vol. 15, no. 4, e0008821

Publication date2021

Abstract

Post-exposure prophylaxis (PEP) is highly effective at preventing human rabies deaths, however access to PEP is limited in many rabies endemic countries. The 2018 decision by Gavi to add human rabies vaccine to its investment portfolio should expand PEP availability and reduce rabies deaths. We explore how geographic access to PEP impacts the rabies burden in Madagascar and the potential benefits of improved provisioning.

Keywords

Accessibility
Surveillance
Public health
Rabies
Madagascar

Affiliation

Research group

Citation (ISO format)

RAJEEV, Malavika et al. How geographic access to care shapes disease burden: The current impact of post-exposure prophylaxis and potential for expanded access to prevent human rabies deaths in Madagascar. In: PLOS Neglected Tropical Diseases, 2021, vol. 15, n° 4, p. e0008821. doi: 10.1371/journal.pntd.0008821