Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial
ContributorsVon Dach-Saouter, Elodie; Albrich, Werner C; Brunel, Anne-Sophie; Prendki, Virginie; Cuvelier, Clémence; Flury, Domenica; Gayet-Ageron, Angèle; Huttner, Benedikt
Published inJAMA (Journal of the American Medical Association), vol. 323, no. 21, p. 2160-2169
Publication date2020
Abstract
Keywords
- Aged
- Aged, 80 and over
- Algorithms
- Anti-Bacterial Agents/administration & dosage/adverse effects
- Bacteremia/drug therapy/microbiology/mortality
- C-Reactive Protein/analysis
- Drug Administration Schedule
- Duration of Therapy
- Female
- Gram-Negative Bacteria
- Gram-Negative Bacterial Infections/drug therapy/mortality
- Humans
- Intention to Treat Analysis
- Male
- Microbial Sensitivity Tests
- Middle Aged
- Multivariate Analysis
- Recurrence
- Regression Analysis
- Treatment Failure
Affiliation
- Faculté de médecine / Centre de recherche clinique
- Faculté de médecine / Section de médecine clinique / Département de médecine
- Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires
- Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie
Citation (ISO format)
VON DACH-SAOUTER, Elodie et al. Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial. In: JAMA (Journal of the American Medical Association), 2020, vol. 323, n° 21, p. 2160–2169. doi: 10.1001/jama.2020.6348
Main files (1)
Article (Published version)
Secondary files (3)
Identifiers
- PID : unige:151567
- DOI : 10.1001/jama.2020.6348
- PMID : 32484534
Commercial URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267846/
ISSN of the journal0098-7484
