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Scientific article
Open access
English

Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial

Published inJAMA (Journal of the American Medical Association), vol. 323, no. 21, p. 2160-2169
Publication date2020
Abstract

Antibiotic overuse drives antibiotic resistance. Gram-negative bacteremia is a common infection that results in substantial antibiotic use.

Keywords
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Anti-Bacterial Agents/administration & dosage/adverse effects
  • Bacteremia/drug therapy/microbiology/mortality
  • C-Reactive Protein/analysis
  • Drug Administration Schedule
  • Duration of Therapy
  • Female
  • Gram-Negative Bacteria
  • Gram-Negative Bacterial Infections/drug therapy/mortality
  • Humans
  • Intention to Treat Analysis
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Multivariate Analysis
  • Recurrence
  • Regression Analysis
  • Treatment Failure
Citation (ISO format)
VON DACH-SAOUTER, Elodie et al. Effect of C-Reactive Protein-Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients With Uncomplicated Gram-Negative Bacteremia: A Randomized Clinical Trial. In: JAMA (Journal of the American Medical Association), 2020, vol. 323, n° 21, p. 2160–2169. doi: 10.1001/jama.2020.6348
Main files (1)
Article (Published version)
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Secondary files (3)
Identifiers
ISSN of the journal0098-7484
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Technical informations

Creation05/03/2021 7:04:00 PM
First validation05/03/2021 7:04:00 PM
Update time03/16/2023 12:33:12 AM
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