Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone

Seners, Pierre; Ben Hassen, Wagih; Lapergue, Bertrand; Arquizan, Caroline; Heldner, Mirjam R.; Henon, Hilde; Perrin, Claire; Strambo, Davide; Cottier, Jean-Philippe; Sablot, Denis; Girard Buttaz, Isabelle; Tamazyan, Ruben; Preterre, Cécile; Agius, Pierre; Laksiri, Nadia; Mechtouff, Laura; Béjot, Yannick; Duong, Duc-Long; Mounier-Vehier, François; Mione, Gioia; Rosso, Charlotte; Lucas, Ludovic; Papassin, Jérémie; Aignatoaie, Andreea; Triquenot, Aude; Carrera, Emmanuel; Niclot, Philippe; Obadia, Alexandre; Lyoubi, Aïcha; Garnier, Pierre; Crainic, Nicolae; Wolff, Valérie; Tracol, Clément; Philippeau, Frédéric; Lamy, Chantal; Soize, Sébastien; Baron, Jean-Claude; Turc, Guillaume; MINOR-STROKE Collaborators

doi:10.1001/jamaneurol.2020.4557

Scientific article

English

Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone

Published inJAMA Neurology, vol. 78, no. 3, p. 321-328

Publication date2021

Abstract

Importance: The best reperfusion strategy in patients with acute minor stroke and large vessel occlusion (LVO) is unknown. Accurately predicting early neurological deterioration of presumed ischemic origin (ENDi) following intravenous thrombolysis (IVT) in this population may help to select candidates for immediate transfer for additional thrombectomy. Objective: To develop and validate an easily applicable predictive score of ENDi following IVT in patients with minor stroke and LVO.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Citation (ISO format)

SENERS, Pierre et al. Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone. In: JAMA Neurology, 2021, vol. 78, n° 3, p. 321–328. doi: 10.1001/jamaneurol.2020.4557

Article (Published version)

Identifiers

PID : unige:151407
DOI : 10.1001/jamaneurol.2020.4557
PMID : 33427887

Commercial URLhttps://jamanetwork.com/journals/jamaneurology/fullarticle/2774466

Journal ISSN2168-6149

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Creation04/05/2021 6:53:00 PM

First validation04/05/2021 6:53:00 PM

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Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone

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