A kinetics-based approach to amyloid PET semi-quantification

Chincarini, A; Peira, E; Corosu, M; Morbelli, S; Bauckneht, M; Capitanio, S; Pardini, M; Arnaldi, D; Vellani, C; D'Ambrosio, D; Garibotto, Valentina; Assal, Frédéric; Paghera, B; Savelli, G; Stefanelli, A; Guerra, U P; Nobili, F

doi:10.1007/s00259-020-04689-y

Scientific article

English

A kinetics-based approach to amyloid PET semi-quantification

ContributorsChincarini, A; Peira, E; Corosu, M; Morbelli, S; Bauckneht, M; Capitanio, S; Pardini, M; Arnaldi, D; Vellani, C; D'Ambrosio, D; Garibotto, Valentina

; Assal, Frédéric; Paghera, B; Savelli, G; Stefanelli, A; Guerra, U P; Nobili, F

Published inEuropean Journal of Nuclear Medicine and Molecular Imaging, vol. 47, no. 9, p. 2175-2185

Publication date2020

Abstract

Purpose: To develop and validate a semi-quantification method (time-delayed ratio, TDr) applied to amyloid PET scans, based on tracer kinetics information.

Keywords

Amyloid PET
Fluorinated tracer
Semi-quantification
Tracer kinetics

UNIGE affiliation entities

UNIGE research groups

Funding

Swiss National Science Foundation - The Biological Basis of Cognitive Impairment due to Suspected Non-Alzheimer's Pathology (SNAP) : Studying the interplay between amyloidosis and tau-related neurodegeneration [169876]

Citation (ISO format)

CHINCARINI, A et al. A kinetics-based approach to amyloid PET semi-quantification. In: European Journal of Nuclear Medicine and Molecular Imaging, 2020, vol. 47, n° 9, p. 2175–2185. doi: 10.1007/s00259-020-04689-y

Article (Published version)

Identifiers

PID : unige:151402
DOI : 10.1007/s00259-020-04689-y
PMID : 31982991

Additional URL for this publicationhttps://link.springer.com/article/10.1007%2Fs00259-020-04689-y

Journal ISSN1619-7070

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Creation21/04/2021 08:23:00

First validation21/04/2021 08:23:00

Update17/01/2025 16:08:48

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A kinetics-based approach to amyloid PET semi-quantification

Purpose: To develop and validate a semi-quantification method (time-delayed ratio, TDr) applied to amyloid PET scans, based on tracer kinetics information.

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