Background: Evidence-based public health requires that research provides policymakers with reliable andaccessible information reflecting the disease threats. We described the scientific production of research inCambodia and assessed to what extent it provides appropriate insights and implications for practice to guidehealth policymakers and managers and knowledge relevant for translation. Methods: We conducted a systematic review of scientific articles published on biomedical research in Cambodia.Regression analysis assessed the trends over time and factors associated with actionable messages in the articles' abstracts.