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Title

Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation

Authors
Blum, Steffen
Aeschbacher, Stefanie
Meyre, Pascal
Kühne, Michael
Rodondi, Nicolas
Beer, Jürg-Hans
Ammann, Peter
Moschovitis, Giorgio
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CollaborationWith : Auberson, Chloé / Bonati, Leo / Ceylan, Selinda / Doerpfeld, Simone / Eken, Ceylan / Girod, Marc / Hämmerle, Peter / Krisai, Philipp / Meyer-Zürn, Christine / Monsch, Andreas U. / Muller, Christian / Springer, Anne / Szucs, Thomas / Voellmin, Gian / Zwimpfer, Leon / Aujesky, Drahomir / Fischer, Urs / Fuhrer, Juerg / Roten, Laurent / Jung, Simon / Mattle, Heinrich / Adam, Luise / Aubert, Carole Elodie / Feller, Martin / Loewe, Axel / Moutzouri, Elisavet / Schneider, Claudio / Flückiger, Tanja / Groen, Cindy / Ehrsam, Lukas / Hellrigl, Sven / Nuoffer, Alexandra / Rakovic, Damiana / Schwab, Nathalie / Wenger, Rylana / Beynon, Christopher / Dillier, Roger / Deubelbeiss, Michèle / Eberli, Franz / Franzini, Christine / Juchli, Isabel / Liedtke, Claudia / Nadler, Jacqueline / Obst, Thayze / Roth, Jasmin / Schlomowitsch, Fiona / Schneider, Xiaoye / Studerus, Katrin / Tynan, Noreen / Weishaupt, Dominik / Müller, Andreas / Fontana, Simone / Kuest, Silke / Scheuch, Karin / Hischier, Denise / Bonetti, Nicole / Grau, Alexandra / Villinger, Jonas / Laube, Eva / Baumgartner, Philipp / Filipovic, Mark / Frick, Marcel / Montrasio, Giulia / Leuenberger, Stefanie / Rutz, Franziska / Auricchio, Angelo / Anesini, Adriana / Camporini, Cristina / Conte, Giulio / Caputo, Maria Luce / Regoli, François / Moccetti, Tiziano / Brenner, Roman / Altmann, David / Gemperle, Michaela / Firmann, Mathieu / Foucras, Sandrine / Rime, Martine / Hayoz, Daniel / Berte, Benjamin / Justi, Virgina / Kellner-Weldon, Frauke / Mehmann, Brigitta / Meier, Sonja / Roth, Myriam / Ruckli-Kaeppeli, Andrea / Russi, Ian / Schmidt, Kai / Young, Mabelle / Zbinden, Melanie / Kobza, Richard / Frangi-Kultalahti, Jane / Pin, Anica / Vicari, Luisa / Ehret, Georg Benedikt / Gallet, Hervé / Guillermet, Elise / Lazeyras, François / Lövblad, Karl-Olof / Perret, Patrick / Tavel, Philippe / Teres Castillo, Cheryl / Shah, Dipen / Lauriers, Nathalie / Méan, Marie / Salzmann, Sandrine / Schläpfer, Jürg / Grêt, Andrea / Novak, Jan / Vitelli, Sandra / Stephan, Frank-Peter / Gallino, Augusto / Di Valentino, Marcello / Witassek, Fabienne / Schwenkglenks, Matthias / Würfel, Jens / Altermatt, Anna / Amann, Michael / Huber, Petra / Ruberte, Esther / Sinnecker, Tim / Zuber, Vanessa / Coslovsky, Michael / Benkert, Pascal / Dutilh, Gilles / Markovic, Milica / Simon, Patrick / Schmid, Ramun
Published in Heart Rhythm. 2021, vol. 18, no. 4, p. 512-519
Abstract The occurrence of congestive heart failure (CHF) hospitalization among patients with atrial fibrillation (AF) is a poor prognostic marker. The purpose of this study was to assess whether insulin-like growth factor-binding protein 7 (IGFBP-7), a marker of myocardial damage, identifies AF patients at high risk for this complication. We analyzed 2 prospective multicenter observational cohort studies that included 3691 AF patients. Levels of IGFBP-7 and N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured from frozen plasma samples at baseline. The primary endpoint was hospitalization for CHF. Multivariable adjusted Cox regression analyses were constructed.
Keywords Atrial fibrillationBiomarkersEpidemiologyHeart failureInsulin-like growth factor-binding protein 7
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PMID: 33278630
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Article (Published version) (366 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Appendix (73 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Other version: https://linkinghub.elsevier.com/retrieve/pii/S1547527120311322
Structures
Research group Ischémie cérébrale et connectivité (801)
Projects FNS: PP00P3_159322
FNS: 33CS30_1148474 and 33CS30_177520
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BLUM, Steffen et al. Insulin-like growth factor-binding protein 7 and risk of congestive heart failure hospitalization in patients with atrial fibrillation. In: Heart Rhythm, 2021, vol. 18, n° 4, p. 512-519. doi: 10.1016/j.hrthm.2020.11.028 https://archive-ouverte.unige.ch/unige:150843

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Deposited on : 2021-04-07

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