en
Scientific article
Review
Open access
English

Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults

Published inEuropean Respiratory Review, vol. 23, no. 134, p. 510-518
Publication date2014
Abstract

Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of deterioration and hospitalisation in the days following the treatment. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based therapy, the overall evaluation of risk-benefit is unlike that of pharmaceutical products; safety aspects, regulatory requirements, study design and effect size assessment may be unfamiliar. The mechanisms of action and optimal patient selection need to be addressed in further rigorous clinical and scientific studies. Bronchial thermoplasty fits in perfectly with the movement to expand personalised medicine in the field of chronic airway disorders. This is a device-based complimentary asthma treatment that must be supported and developed in order to meet the unmet needs of modern severe asthma management. The mechanisms of action and the type of patients that benefit from bronchial thermoplasty are the most important challenges for bronchial thermoplasty in the future.

Keywords
  • Adolescent
  • Adult
  • Aged
  • Asthma/physiopathology/therapy
  • Bronchi/physiopathology
  • Bronchoscopy/adverse effects/instrumentation/methods
  • Catheters
  • Humans
  • Hyperthermia, Induced/adverse effects/instrumentation/methods
  • Middle Aged
  • Patient Selection
  • Severity of Illness Index
  • Treatment Outcome
  • Young Adult
Citation (ISO format)
DOMBRET, Marie-Christine et al. Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults. In: European Respiratory Review, 2014, vol. 23, n° 134, p. 510–518. doi: 10.1183/09059180.00005114
Main files (1)
Article (Published version)
Identifiers
ISSN of the journal0905-9180
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