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Scientific article
Open access
English

The DNA Sequence Change Resulting from the IQ1 Mutation, which Greatly Increases Promoter Strength

Published inMolecular and General Genetics, vol. 183, no. 3, p. 559-560
Publication date1981
Abstract

DNA sequencing shows that the mutational alteration resulting from IQ1 is a deletion of 15 base pairs in the lacI promoter. The deletion creates a greatly improved — 35 homology region, explaining the 50–100-fold increase in lac repressor synthesis.

Funding
  • Swiss National Science Foundation - 3.493.0.79
Citation (ISO format)
CALOS, Michèle P., MILLER, Jeffrey H. The DNA Sequence Change Resulting from the <i>I<sup>Q1</sup></i> Mutation, which Greatly Increases Promoter Strength. In: Molecular and General Genetics, 1981, vol. 183, n° 3, p. 559–560. doi: 10.1007/BF00268783
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Article (Published version)
Identifiers
ISSN of the journal0026-8925
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