Adherence to prescribed medication is suboptimal in 50% of the chronic population,resulting in negative medical and economic outcomes. With the widespread use of mobilephones worldwide, medication adherence apps for mobile phones become promisingmedication adherence aids thanks to simplicity, user-friendliness, and accessibility forthe public. Yet, until today, there is insufficient evidencein favor of using mobilehealth (mHealth) apps to increase medication adherence. This study aims to developa methodology for scientific and end-user (patient) mHealthevaluation (a) to identifymedication adherence apps search terms, (b) to evaluate identified apps based onscientific criteria, and (c) to report best smartphone apps evaluated by patients.