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Title

Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine

Authors
Shaffer, Juanita
Means, Terry K
Alexander, Stephen
Dombkowski, David
Dey, Bimalangshu R
McAfee, Steven
Ballen, Karen K
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Published in Experimental Hematology. 2007, vol. 35, no. 7, p. 1140-1152
Abstract We have evaluated T-cell reconstitution and reactivity in patients receiving nonmyeloablative haploidentical hematopoietic cell transplantation (HCT) protocols involving an anti-CD2 monoclonal antibody (MEDI 507) to treat chemorefractory hematopoietic malignancies.
Keywords Antibodies, Monoclonal/pharmacologyAntibodies, Monoclonal, HumanizedAntigens, CD/analysisAntigens, Differentiation/analysisCD2 Antigens/immunologyCTLA-4 AntigenForkhead Transcription Factors/analysisHematopoietic Stem Cell TransplantationHistocompatibility TestingHumansInterferon-gamma/geneticsT-Lymphocytes, Regulatory/physiologyTransforming Growth Factor beta/geneticsTransplantation ChimeraVidarabine/analogs & derivatives/pharmacology
Identifiers
PMID: 17588483
Full text
Research group Transplantation immunologie et osteoimmunologie (561)
Citation
(ISO format)
SHAFFER, Juanita et al. Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine. In: Experimental Hematology, 2007, vol. 35, n° 7, p. 1140-1152. doi: 10.1016/j.exphem.2007.03.018 https://archive-ouverte.unige.ch/unige:149592

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Deposited on : 2021-02-23

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