Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer's Disease

Marizzoni, Moira; Cattaneo, Annamaria; Mirabelli, Peppino; Festari, Cristina; Lopizzo, Nicola; Nicolosi, Valentina; Mombelli, Elisa; Mazzelli, Monica; Luongo, Delia; Naviglio, Daniele; Coppola, Luigi; Salvatore, Marco; Frisoni, Giovanni

doi:10.3233/JAD-200306

Scientific article

English

Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer's Disease

ContributorsMarizzoni, Moira; Cattaneo, Annamaria; Mirabelli, Peppino; Festari, Cristina; Lopizzo, Nicola; Nicolosi, Valentina; Mombelli, Elisa; Mazzelli, Monica; Luongo, Delia; Naviglio, Daniele; Coppola, Luigi; Salvatore, Marco; Frisoni, Giovanni

Published inJournal of Alzheimer's Disease, vol. 78, no. 2, p. 683-697

Publication date2020

Abstract

Metagenomic data support an association between certain bacterial strains and Alzheimer's disease (AD), but their functional dynamics remain elusive.

Keywords

Brain amyloidosis
Inflammation
Lipopolysaccharide
Microbiota
Short chain fatty acids

Affiliation

Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

Research group

Troubles de mémoire et maladie d'Alzeimer (935)

Citation (ISO format)

MARIZZONI, Moira et al. Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer’s Disease. In: Journal of Alzheimer’s Disease, 2020, vol. 78, n° 2, p. 683–697. doi: 10.3233/JAD-200306

Article (Published version)

Identifiers

PID : unige:149475
DOI : 10.3233/JAD-200306
PMID : 33074224

ISSN of the journal1387-2877

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Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer's Disease

Metagenomic data support an association between certain bacterial strains and Alzheimer's disease (AD), but their functional dynamics remain elusive.

Technical informations