Scientific article
Open access

A 20S Particle Ubiquitous from Yeast to Human

Published inJournal of Molecular Evolution, vol. 25, no. 2, p. 141-150
Publication date1987

We have purified and characterized a particle sedimenting at 20S from the postribosomal fraction of yeast, wheat germ,Drosophila melanogaster tissue culture cells, chicken embryo fibroblasts, rabbit reticulocyte lysate, and HeLa cells. Most of the protein constituents of the 20S particle have molecular weights of 20–35 kd and differ between species; however, some do have similar molecular weights and isoelectric points, suggesting they are related. Several low-molecular-weight RNAs, distinct from tRNAs, co-purify with the particle isolated from all these species and show increasingly more complex patterns ascending the arbitrary order from yeast to human (yeast, plant, insect, bird, and mammals). InDrosophila, we present evidence that these small RNAs are tightly associated with this 20S structure.

  • 20S particle
  • Prosome
  • Evolution
  • Small cytoplasmic RNAs
  • Heat shock proteins
Citation (ISO format)
ARRIGO, André-Patrick et al. A 20S Particle Ubiquitous from Yeast to Human. In: Journal of Molecular Evolution, 1987, vol. 25, n° 2, p. 141–150. doi: 10.1007/BF02101756
Main files (1)
Article (Published version)
ISSN of the journal0022-2844

Technical informations

Creation02/16/2021 12:05:00 PM
First validation02/16/2021 12:05:00 PM
Update time03/16/2023 12:06:17 AM
Status update03/16/2023 12:06:16 AM
Last indexation02/12/2024 12:02:08 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack