en
Scientific article
English

One-Step Catalytic Asymmetric Synthesis of Configurationally Stable Tröger Bases

Published inAngewandte Chemie, vol. 50, no. 16, p. 3677-3680
Publication date2011
Abstract

Bridging the gap: Configurationally stable ethano-bridged Tröger bases have been prepared in a single step by the direct rhodium(II)-catalyzed reaction of methano-bridged Tröger bases and diazo esters (see scheme). The process is general, enantiospecific, diastereoselective (with introduction of a new quaternary carbon center), and regioselective.

Keywords
  • Carbenoids
  • Diazo compounds
  • Rearrangement
  • Rhodium
  • Tröger bases
Citation (ISO format)
SHARMA, Ankit et al. One-Step Catalytic Asymmetric Synthesis of Configurationally Stable Tröger Bases. In: Angewandte Chemie, 2011, vol. 50, n° 16, p. 3677–3680. doi: 10.1002/anie.201100134
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1433-7851
571views
0downloads

Technical informations

Creation04/05/2011 2:02:00 PM
First validation04/05/2011 2:02:00 PM
Update time03/14/2023 4:15:02 PM
Status update03/14/2023 4:15:02 PM
Last indexation01/15/2024 10:18:05 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack