Commentary: Prevalence of Alternative Diagnoses and Implications for Management in Idiopathic Normal Pressure Hydrocephalus Patients

Allali, Gilles; Uginet, Marjolaine; Sveikata, Lukas

doi:10.1093/neuros/nyaa218

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Title		Commentary: Prevalence of Alternative Diagnoses and Implications for Management in Idiopathic Normal Pressure Hydrocephalus Patients
Authors		Allali, Gilles Uginet, Marjolaine Sveikata, Lukas
Published in		Neurosurgery. 2020, vol. 87, no. 5, p. E545-E546
Abstract		Idiopathic normal pressure hydrocephalus (iNPH)–the leading cause of reversible dementia in aging–affects 5.9% of adults older than 80.1 The clinical presentation of iNPH combining gait disorders, impaired cognition (ie, poor executive function and memory), and urinary incontinence is unspecific in aging and frequently found in alternate neurological and non-neurological conditions, such as Parkinson disease or vascular dementia, also called iNPH mimics or iNPH mimickers. In the Geneva Normal Pressure Hydrocephalus cohort, we reported a prevalence of 45.6% of iNPH mimics among a cohort of 125 patients with suspicion of iNPH.
Keywords		Normal pressure hydrocephalus — Cerebral amyloid angiopathy — Cerebral microbleeds — Dementia — Cerebrovascular disease
Identifiers		DOI: 10.1093/neuros/nyaa218 PMID: 32470984
Full text		Article (Published version) (254 Kb) - Limited access to UNIGE Other version: https://academic.oup.com/neurosurgery/article/87/5/E545/5848680
Structures		Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques
Project		Swiss National Science Foundation: 320030_173153
Citation (ISO format)		ALLALI, Gilles, UGINET, Marjolaine, SVEIKATA, Lukas. Commentary: Prevalence of Alternative Diagnoses and Implications for Management in Idiopathic Normal Pressure Hydrocephalus Patients. In: Neurosurgery, 2020, vol. 87, n° 5, p. E545-E546. doi: 10.1093/neuros/nyaa218 https://archive-ouverte.unige.ch/unige:148765