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Polymorphisme des HLA loci de classe l, HL A-A, -B et -C, dans la population Mandenka du Sénégal Oriental (Polymorphism of HLA class I loci HLA-A, -B, -C, in the Mandenka population from eastern Senegal)

Schreiber, Y.
Shi-Isaac, X.
Epelbouin, A.
Published in Comptes Rendus de l'Académie des Sciences. III, Sciences de la Vie. 1992, vol. 314, no. 13, p. 573-8
Abstract A sample of 162 Mandenkalu from Eastern Senegal has been typed for three HLA class I loci: HLA-A, -B and -C. The Mandenka population presents a very high genetic variability with 15 alleles for locus A, 24 alleles for locus B, and at least 8 alleles for locus C. The calculated heterozygosities for the three loci A, B, and C are respectively 0.884, 0.944 and 0.829. The Mandenkalu allelic frequencies are close to that found in other sub-Saharan populations. They show, however, some peculiarities like the occurrence of the Bw 56 allele and the high frequencies of both B5 and B35.
Keywords AlleleHuman geneticsPhenotypeSenegal PolymorphismMandenka
Stable URL https://archive-ouverte.unige.ch/unige:14854
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PMID: 1393737
Research group Unité d’anthropologie

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Deposited on : 2011-03-25

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