Scientific article

Iridocorneal angle assessment after laser iridotomy with swept-source optical coherence tomography

Published inJournal of Glaucoma, vol. 29, no. 11, p. 1030-1035
Publication date2020

Aim: To investigate the reliability of anterior chamber angle (ACA) measurements in narrow angles and assess the effect of laser peripheral iridotomy (LPI) on these measurements using novel swept-source optical coherence tomography (SS-OCT) technology. Materials and Methods: In this prospective observational study, patients with gonioscopically narrow angles were enrolled and scheduled for prophylactic LPI. Twelve ACA sections were obtained in each eye using SS-OCT (ANTERION, Heidelberg Engineering, Germany) before and after Nd:YAG LPI. A built-in algorithm calculated ACA measurements after manual identification of the scleral spur and ACA recess. Eight ACA parameters were evaluated: ACA (ACA 500, ACA 750); scleral spur angle (SSA 500, SSA 750); angle opening distance (AOD 500, AOD 750); and trabecular iris space area (TISA 500, TISA 750). The effect of LPI was assessed for each parameter, both nasally and temporally. Results: Ten patients (18 eyes) were enrolled (mean age, 61.8 +/- 13.6 y; 60.0% female individuals). On average, the ACA was wider nasally than temporally (P=0.004). LPI significantly widened the ACA (range, 26.7-29.4%; P<0.05). ACA 500 increased by 29.4% (P<0.001), ACA 750 by 29.2% (P=0.002), SSA 500 by 27.3% (P=0.003), SSA 750 by 28.1% (P=0.001), AOD 500 by 28.6% (P=0.009), AOD 750 by 28.6% (P=0.003), TISA 500 by 27.3% (P=0.004), and TISA 750 by 26.7% (P=0.200). Conclusions: SS-OCT ANTERION imaging can be used to reliably measure ACA before and after LPI. ACA, AOD, SSA, and TISA are all valid ACA measurement methods.

  • Angle closure
  • Anterior chamber angle
  • Glaucoma
  • Laser peripheral iridotomy
  • LPI
  • Narrow angle
  • Primary angle-closure glaucoma
  • OCT
Affiliation Not a UNIGE publication
Citation (ISO format)
MEDURI, Enrico et al. Iridocorneal angle assessment after laser iridotomy with swept-source optical coherence tomography. In: Journal of Glaucoma, 2020, vol. 29, n° 11, p. 1030–1035. doi: 10.1097/IJG.0000000000001654
Main files (1)
Article (Published version)
ISSN of the journal1057-0829

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