In strictly one-dimensional systems, repulsive interactions tend to reduce particle mobility on a lattice. Therefore, the Drude weight, controlling the divergence at zero-frequency of optical conductivities in perfect conductors, is lower than in noninteracting cases. We show that this is not the case when extending to quasi-one-dimensional ladder systems. Relying on bosonization, perturbative and matrix product states (MPS) calculations, we show that nearest-neighbor interactions and magnetic fluxes provide a bias between back- and forward-scattering processes, leading to linear corrections to the Drude weight in the interaction strength. As a consequence, Drude weights counterintuitively increase (decrease) with repulsive (attractive) interactions. Our findings are relevant for the efficient tuning of Drude weights in the framework of ultracold atoms trapped in optical lattices and equally affect topological edge states in condensed matter systems.