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Title

Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents

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Published in Emerging infectious diseases. 2020, vol. 26, no. 10, p. 2494-2497
Abstract Children do not seem to drive transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We isolated culture-competent virus in vitro from 12 (52%) of 23 SARS-CoV-2-infected children; the youngest was 7 days old. Our findings show that symptomatic neonates, children, and teenagers shed infectious SARS-CoV-2, suggesting that transmission from them is plausible.
Keywords AdolescentBetacoronavirus/isolation & purification/physiologyCOVID-19Cell LineChildChild, PreschoolCoronavirus Infections/diagnosis/transmissionFemaleHumansInfantInfant, NewbornMaleNasopharynx/virologyPandemicsPneumonia, Viral/diagnosis/transmissionRNA, Viral/analysisSARS-CoV-2Viral LoadVirus CultivationVirus Replication
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PMID: 32603290
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Research groups Groupe Laurent Kaiser (virologie clinique) (668)
Emerging viruses (993)
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(ISO format)
L'HUILLIER, Arnaud et al. Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents. In: Emerging Infectious Diseases, 2020, vol. 26, n° 10, p. 2494-2497. doi: 10.3201/eid2610.202403 https://archive-ouverte.unige.ch/unige:146962

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Deposited on : 2021-01-07

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