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Title

Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents
Authors
L'Huillier, Arnaud
Torriani, Giulia
Pigny, Fiona
Kaiser, Laurent
Eckerle, Isabella Anne
Published in Emerging infectious diseases. 2020, vol. 26, no. 10, p. 2494-2497
Abstract Children do not seem to drive transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We isolated culture-competent virus in vitro from 12 (52%) of 23 SARS-CoV-2-infected children; the youngest was 7 days old. Our findings show that symptomatic neonates, children, and teenagers shed infectious SARS-CoV-2, suggesting that transmission from them is plausible.
Keywords Adolescent — Betacoronavirus/isolation & purification/physiology — COVID-19 — Cell Line — Child — Child, Preschool — Coronavirus Infections/diagnosis/transmission — Female — Humans — Infant — Infant, Newborn — Male — Nasopharynx/virology — Pandemics — Pneumonia, Viral/diagnosis/transmission — RNA, Viral/analysis — SARS-CoV-2 — Viral Load — Virus Cultivation — Virus Replication
Identifiers
PMID: 32603290
Full text
Article (Published version) (338 Kb) - public document Free access
Other version: https://wwwnc.cdc.gov/eid/article/26/10/20-2403_article
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine
Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research groups Groupe Laurent Kaiser (virologie clinique) (668)
Emerging viruses (993)
Citation
(ISO format) 		L'HUILLIER, Arnaud et al. Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents. In: Emerging Infectious Diseases, 2020, vol. 26, n° 10, p. 2494-2497. doi: 10.3201/eid2610.202403 https://archive-ouverte.unige.ch/unige:146962

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Deposited on : 2021-01-07

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