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Scientific article
Open access
English

Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents

Published inEmerging Infectious Diseases, vol. 26, no. 10, p. 2494-2497
Publication date2020
Abstract

Children do not seem to drive transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We isolated culture-competent virus in vitro from 12 (52%) of 23 SARS-CoV-2-infected children; the youngest was 7 days old. Our findings show that symptomatic neonates, children, and teenagers shed infectious SARS-CoV-2, suggesting that transmission from them is plausible.

Keywords
  • Adolescent
  • Betacoronavirus/isolation & purification/physiology
  • COVID-19
  • Cell Line
  • Child
  • Child, Preschool
  • Coronavirus Infections/diagnosis/transmission
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Nasopharynx/virology
  • Pandemics
  • Pneumonia, Viral/diagnosis/transmission
  • RNA, Viral/analysis
  • SARS-CoV-2
  • Viral Load
  • Virus Cultivation
  • Virus Replication
Citation (ISO format)
L’HUILLIER, Arnaud et al. Culture-Competent SARS-CoV-2 in Nasopharynx of Symptomatic Neonates, Children, and Adolescents. In: Emerging Infectious Diseases, 2020, vol. 26, n° 10, p. 2494–2497. doi: 10.3201/eid2610.202403
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1080-6040
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68downloads

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Creation12/14/2020 12:58:00 PM
First validation12/14/2020 12:58:00 PM
Update time03/15/2023 11:47:46 PM
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