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Title

Sustained response to pembrolizumab without prior chemotherapy in high-grade serous ovarian carcinoma with CSMD3 mutation

Authors
Terzic, Julie
Published in Gynecologic Oncology Reports. 2020, vol. 33, p. 100600
Abstract •Metastatic CSMD3 mutated HGSOC showed objective and sustained response to pembrolizumab.•The tumor was massively infiltrated by CD8+ T cells while PD-L1 TPS was at 10%.•CSMD3 mutated HGSOC showed up-regulation of CCL5 and CXCL9.
Identifiers
PMID: 32613071
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Article (Published version) (1.6 MB) - public document Free access
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Research group Métastases du foie (657)
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TERZIC, Julie et al. Sustained response to pembrolizumab without prior chemotherapy in high-grade serous ovarian carcinoma with CSMD3 mutation. In: Gynecologic Oncology Reports, 2020, vol. 33, p. 100600. doi: 10.1016/j.gore.2020.100600 https://archive-ouverte.unige.ch/unige:146865

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Deposited on : 2020-12-22

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