Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome

Kallio, Merja; van der Zwaag, Anne-Sea; Waldmann, Andreas D; Rahtu, Marika; Miedema, Martijn; Papadouri, Thalia; van Kaam, Anton H; Rimensberger, Peter; Bayford, Richard; Frerichs, Inéz

doi:10.1159/000502612

Scientific article

English

Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome

ContributorsKallio, Merja; van der Zwaag, Anne-Sea; Waldmann, Andreas D; Rahtu, Marika; Miedema, Martijn; Papadouri, Thalia; van Kaam, Anton H; Rimensberger, Peter; Bayford, Richard; Frerichs, Inéz

Published inNeonatology, vol. 116, no. 4, p. 385-389

Publication date2019

Abstract

Exogenous surfactant administration is an essential part of respiratory distress syndrome treatment in preterm infants. Current guidelines recommend the first dose to be given as early as possible, followed by an additional dose if symptoms persist. The effect of additional dosing on regional ventilation and lung volume has not been investigated so far.

Keywords

Blood Gas Analysis
Electric Impedance
Europe
Female
Gestational Age
High-Frequency Ventilation/methods
Humans
Infant, Newborn
Infant, Premature
Intensive Care Units, Neonatal
Lung/physiopathology
Lung Volume Measurements
Male
Prospective Studies
Pulmonary Surfactants/administration & dosage/therapeutic use
Respiratory Distress Syndrome, Newborn/physiopathology/therapy
Tidal Volume
Tomography

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research groups

Maladies pulmonaires aigues et pathologies cardiaques congénitales (697)

Funding

Autre - Swiss State Secretariat for education, research and Innovation (SERI) under contract number 15.0342–1
European Commission - Continuous Regional Analysis Device for neonate Lung [668259]

Citation (ISO format)

KALLIO, Merja et al. Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome. In: Neonatology, 2019, vol. 116, n° 4, p. 385–389. doi: 10.1159/000502612

Article (Published version)

Identifiers

PID : unige:146832
DOI : 10.1159/000502612
PMID : 31505498

Additional URL for this publicationhttps://www.karger.com/Article/Abstract/502612

Datasets

https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Initial_Observations_on_the_Effect_of_Repeated_Surfactant_Dose_on_Lung_Volume_and_Ventilation_in_Neonatal_Respiratory_Distress_Syndrome/9792662

Journal ISSN1661-7800

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Update15/03/2023 23:45:39

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Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome

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