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Title

Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome

Authors
Kallio, Merja
van der Zwaag, Anne-Sea
Waldmann, Andreas D
Rahtu, Marika
Miedema, Martijn
Papadouri, Thalia
van Kaam, Anton H
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Published in Neonatology. 2019, vol. 116, no. 4, p. 385-389
Abstract Exogenous surfactant administration is an essential part of respiratory distress syndrome treatment in preterm infants. Current guidelines recommend the first dose to be given as early as possible, followed by an additional dose if symptoms persist. The effect of additional dosing on regional ventilation and lung volume has not been investigated so far.
Keywords Blood Gas AnalysisElectric ImpedanceEuropeFemaleGestational AgeHigh-Frequency Ventilation/methodsHumansInfant, NewbornInfant, PrematureIntensive Care Units, NeonatalLung/physiopathologyLung Volume MeasurementsMaleProspective StudiesPulmonary Surfactants/administration & dosage/therapeutic useRespiratory Distress Syndrome, Newborn/physiopathology/therapyTidal VolumeTomography
Identifiers
PMID: 31505498
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Structures
Research group Maladies pulmonaires aigues et pathologies cardiaques congénitales (697)
Projects Swiss State Secretariat for education, research and Innovation (SERI) under contract number 15.0342–1
H2020: CRADL
Citation
(ISO format)
KALLIO, Merja et al. Initial Observations on the Effect of Repeated Surfactant Dose on Lung Volume and Ventilation in Neonatal Respiratory Distress Syndrome. In: Neonatology, 2019, vol. 116, n° 4, p. 385-389. doi: 10.1159/000502612 https://archive-ouverte.unige.ch/unige:146832

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Deposited on : 2020-12-21

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