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Title

Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

Authors
Vermunt, Lisa
Sikkes, Sietske A M
van den Hout, Ardo
Handels, Ron
Bos, Isabelle
van der Flier, Wiesje M
Kern, Silke
Ousset, Pierre-Jean
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CollaborationWith : Zekry Berger, Dina Selma
Published in Alzheimer's & Dementia. 2019, vol. 15, no. 7, p. 888-898
Abstract We estimated the age-specific duration of the preclinical, prodromal, and dementia stages of Alzheimer's disease (AD) and the influence of sex, setting, apolipoprotein E (APOE) genotype, and cerebrospinal fluid tau on disease duration.
Keywords AgedAllelesAlzheimer Disease/genetics/pathologyAmyloidApolipoprotein E4/geneticsBiomarkers/cerebrospinal fluidCognitive Dysfunction/pathologyDisease ProgressionFemaleGenotypeHumansLongitudinal StudiesMalePositron-Emission TomographyProdromal SymptomsSex FactorsTime Factorstau Proteins/cerebrospinal fluid
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PMID: 31164314
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VERMUNT, Lisa et al. Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype. In: Alzheimer's & Dementia, 2019, vol. 15, n° 7, p. 888-898. doi: 10.1016/j.jalz.2019.04.001 https://archive-ouverte.unige.ch/unige:146823

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Deposited on : 2020-12-18

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