UNIGE document Scientific Article
previous document  unige:146382  next document
add to browser collection
Title

Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses

Authors
Slater, Tessa
Chang, Kin-Chow
Published in Virology Journal. 2018, vol. 15, no. 1, 68
Abstract With the recent discovery of novel H17N10 and H18N11 influenza viral RNA in bats and report on high frequency of avian H9 seroconversion in a species of free ranging bats, an important issue to address is the extent bats are susceptible to conventional avian and human influenza A viruses. To this end, three bat species (Eidolon helvum, Carollia perspicillata and Tadarida brasiliensis) of lungepithelial cells were separately infected with two avian and two human influenza viruses to determine their relativehost innate immune resistance to infection.
Keywords InfluenzaBatsEpithelial cellsHost resistanceInnate immunityInflammationAnimalsCell SurvivalCells, CulturedChiropteraDogsEpithelial Cells/virologyGene ExpressionHost SpecificityInfluenza A virus/classification/immunologyLung/cytology/immunologyMadin Darby Canine Kidney CellsNeuraminidase/pharmacologyOrthomyxoviridae Infections/virologyReceptors, Virus/metabolismViral Proteins/geneticsVirus Release/drug effectsVirus Replication
Identifiers
PMID: 29636078
Full text
Structures
Research groups Groupe Laurent Kaiser (virologie clinique) (668)
Emerging viruses (993)
Citation
(ISO format)
SLATER, Tessa, ECKERLE, Isabella Anne, CHANG, Kin-Chow. Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses. In: Virology Journal, 2018, vol. 15, n° 1, p. 68. doi: 10.1186/s12985-018-0979-6 https://archive-ouverte.unige.ch/unige:146382

89 hits

28 downloads

Update

Deposited on : 2020-12-11

Export document
Format :
Citation style :